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Two Sheffield women have been arrested in relation to a suspicious item being found at a home in a street in Darnall.
Police say they found the item during a house search and took the decision to evacuate the area.
About 40 homes were evacuated on Uttley Close within a 100-metre cordon as a precaution following advice from the Army's bomb squad.
Police said two women from Sheffield had been arrested in connection with the discovery and were in custody.
Regarding the incident, Chief Superintendent Stuart Barton said: "The suspicious item was found during a search of a property and we are following standard procedures to ensure the safety of the nearby residents and officers at the scene.
"We apologise for any inconvenience this may cause to local residents.
"These precautionary measures are in place to ensure safety and we will be in continual contact with those affected until they are able to return to their homes."