England beat India on the fourth day of the fourth Test in Southampton to win the series 3-1.
Man of the match Moeen Ali, on his return to the side, ended with 4-71 to complete match figures of 9-134 to go with 40 runs in England's first innings.
The victory extends a run during which England have lost only one home series since 2012.
They take a 3-1 lead to the fifth and final Test, which begins on Friday at The Oval.